Optical measurement of neural activity using surface plasmon resonance.
نویسندگان
چکیده
We demonstrate that surface plasmon resonance (SPR) is applicable to the optical detection of neural signals. A low-noise SPR sensor was developed as a label- and artifact-free method for the extracellular recording of neural activity. The optical responses obtained from a rat sciatic nerve were highly correlated with simultaneously recorded electrical responses. Additional studies with stimulation intensity and lidocaine further confirmed that the optically measured signals originated from neural activities.
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عنوان ژورنال:
- Optics letters
دوره 33 9 شماره
صفحات -
تاریخ انتشار 2008